Time flies when we’re having fun. NFL Week 3 odds are here with another week packed with football betting action.
Sunday’s afternoon’s slate was headlined by the Dallas Cowboys’ clash with the Baltimore Ravens, while Sunday Night Football saw Patrick Mahomes and the Kansas City Chiefs take on Kirk Cousins (off a rare prime-time win) and the Atlanta Falcons.
Week 3 betting closes out with an intriguing Monday night doubleheader of Jaguars vs. Bills and Commanders vs. Bengals.
Let’s look at the current NFL odds for Week 3 heading into kickoff on Sunday, September 22.
NFL Week 3 Odds
These are the current NFL odds for Week 3, headlined by a late-window showdown between the Baltimore Ravens and Dallas Cowboys.
Jaguars vs. Bills odds
Opening line
- Bills -5.5
- Over/Under 46.5
- View full Jaguars vs. Bills odds and matchup
- Read our Jaguars vs. Bills picks and predictions
The first of two Monday Night Football games in Week 3 opened with Buffalo between -5 and -6, with early play on the Bills running this spread to -6.5 before dropping to as low as -4.5 on Sunday morning. This total opened at 46.5 with Jacksonville struggling to score points and now traveling to Orchard Park in primetime. The Jaguars will be without TE Evan Engram for Week 3, dropping this total to 45.5 O/U.
Also see: full Monday Night Football odds